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Table 1 Baseline characteristics of the all population according to FPG quintiles

From: J-shape relationship between normal fasting plasma glucose and risk of type 2 diabetes in the general population: results from two cohort studies

 

Total

Q1(≤ 4.44)

Q2(4.44–4.78)

Q3(4.78–5.04)

Q4(5.04–5.35)

Q5(≥ 5.35)

P-value

N

220104

44,021

44,021

44,020

444,021

44,021

 

Age (years)

41.8 ± 12.2

39.5 ± 11.0

40.3 ± 11.7

41.0 ± 11.9

42.5 ± 12.3

45.9 ± 13.1

 < 0.001

Sex

 < 0.001

 Women

100647 (45.7)

22,647 (51.4)

22,565 (51.3)

20,917 (47.5)

18,787 (42.7)

15,731 (35.7)

 

 Men

119457 (54.3)

21,374 (48.6)

21,456 (48.7)

23,103 (52.5)

25,234 (57.3)

28,290 (64.3)

Country

 < 0.001

 Chinese

204640 (93.0)

43,468 (98.7)

41,540 (94.4)

41,149 (93.5)

39,436 (89.6)

39,047 (88.7)

 

 Japanese

15464 ( 7.0)

553 (1.3)

2481 (5.6)

2871 (6.5)

4585 (10.4)

4974 (11.3)

 BMI (kg/m2)

23.1 ± 3.3

22.4 ± 3.2

22.6 ± 3.2

22.9 ± 3.3

23.3 ± 3.3

24.1 ± 3.3

 < 0.001

 SBP (mmHg)

118.3 ± 16.1

114.8 ± 15.1

116.2 ± 15.5

117.6 ± 15.7

119.6 ± 16.0

123.6 ± 16.7

 < 0.001

 DBP (mmHg)

73.8 ± 10.7

72.5 ± 10.5

72.4 ± 10.5

73.2 ± 10.6

74.3 ± 10.6

76.6 ± 10.9

 < 0.001

 FPG (mmol/L)

4.9 ± 0.5

4.1 ± 0.3

4.6 ± 0.1

4.9 ± 0.1

5.2 ± 0.1

5.6 ± 0.2

 < 0.001

 TC (mmol/L)

4.7 ± 0.9

4.6 ± 0.9

4.6 ± 0.9

4.7 ± 0.9

4.8 ± 0.9

4.9 ± 0.9

 < 0.001

 TG (mmol/L)

1.0 (0.7, 1.5)

1.0 (0.7, 1.4)

1.0 (0.7, 1.4)

1.0 (0.7, 1.5)

1.1 (0.7, 1.6)

1.2 (0.8, 1.8)

 < 0.001

 ALT (U/L)

18.0 (12.9, 26.8)

16.7 (12.0, 25.0)

16.9 (12.0, 24.9)

17.3 (12.6, 26.0)

18.0 (13.0, 27.0)

20.0 (14.4, 30.4)

 

Hypertension

 < 0.001

 No

192301 (87.4)

40,063 (91)

39,697 (90.2)

38,987 (88.6)

38,104 (86.6)

35,450 (80.5)

 

 Yes

27,803 (12.6)

3958 (9)

4324 (9.8)

5033 (11.4)

5917 (13.4)

8571 (19.5)

Smoking

 < 0.001

 No

55,798 (25.4)

9683 (22)

10,310 (23.4)

10,860 (24.7)

12,388 (28.1)

12,557 (28.5)

 

 Yes

17,451 ( 7.9)

2618 (5.9)

2713 (6.2)

3137 (7.1)

3892 (8.8)

5091 (11.6)

 Unknown

146855 (66.7)

31,720 (72.1)

30,998 (70.4)

30,023 (68.2)

27,741 (63)

26,373 (59.9)

Drinking

 < 0.001

 No

57,046 (25.9)

10,829 (24.6)

10,595 (24.1)

11,085 (25.2)

12,133 (27.6)

12,404 (28.2)

 

 Yes

16,203 ( 7.4)

1472 (3.3)

2428 (5.5)

2912 (6.6)

4147 (9.4)

5244 (11.9)

 Unknown

146855 (66.7)

31,720 (72.1)

30,998 (70.4)

30,023 (68.2)

27,741 (63)

26,373 (59.9)

  1. Measures are expressed as mean ± SD and median (IQR), and counts are expressed as n (%)
  2. Bold values indicate the statistically significant P values
  3. Continuous variables were compared between groups using ANOVA and Kruskal–Wallis analysis, with the chi-square test used for count data
  4. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, TC total cholesterol, TG triglyceride, ALT alanine aminotransferase
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Journal of Translational Medicine

ISSN: 1479-5876

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