Fig. 4
Scheme of photothermal gold nanoparticles and related application example. A Scheme of gold nanorod treating Alzheimer's disease. AuNRs can bind with CeO2 and Aβ-targeted inhibitory peptides to target Aβ fibrils through photocatalysis and photothermal effect, which was used in multi-modal therapy of Alzheimer’s disease [107]. Copyright 2022, American Chemical Society and its reproduced permission granted. B Structural pattern diagram of nanoparticles containing a photothermal material (gold). Composite nanoparticles modified with protective molecules can flow through the bloodstream and cross the blood–brain barrier. Under NIR laser irradiation, gold particles undergo photothermal conversion, and the heat can be generated to dissolve the heat-sensitive materials used to construct the vehicle, so that the drugs can be released to act on neurons