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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: P2RX7 promotes osteosarcoma progression and glucose metabolism by enhancing c-Myc stabilization

Fig. 3

P2RX7 promoted proliferation, migration and invasion of osteosarcoma cells in vitro. a, f Proliferation of osteosarcoma cells analyzed by CCK8. b, g Wound healing assay was performed to evaluate cell migration in P2RX7 wild -type (WT) and knockout (KO) cells. c, h The invasiveness of osteosarcoma cells with P2RX7 knockout or not. d, i Cell cycle analysis by flowcytometry in P2RX7 WT and KO cells. e, j The expressions of proliferation-related and invasion-related genes assessed by qRT-PCR and immunoblot analyses. Data are shown as mean ± standard deviation (SD). *p < 0.05, **p < 0.01, ***p < 0.001 versus corresponding P2RX7 WT group

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