Fig. 2

HT29 xenograft tumors in two mouse models. A The workflow of HT29 xenograft tumors in mouse models. B In the C57BL/6 mouse model, comparison of diabetic mice and normal mice, and tumors dissected from diabetic mice and normal mice implanted with HT29 cells, which were treated with lactoferrin (LF), NT5DC3 protein (NT), HKDC1 antibody (HK), or their combinations. C In BALB/c nude mouse model, comparison of diabetic mice and normal mice, and tumors dissected from diabetic mice and normal mice implanted with HT29 cells, which were treated with LF, NT, or their combinations. D The average tumor weights of diabetic mice and normal mice in the C57BL/6 mouse model. E The average tumor weights of diabetic mice and normal mice in the BALB/c nude mouse model. The tumor group stands for the control. The above data (D, E) are presented as mean ± SD, *P < 0.05 compared with the control (n = 5)