Fig. 4
A 58-year-old male patient with left temporal glioblastoma, WHO grade IV. A, B MRI axial T2W and T2-FLAIR sequences showed tumor entity present as mixed hypersignal with severe peritumoral edema. And the tumor boundary was blurred. C HE staining showed significantly increased cell density, nucleoli were obvious, and karyokinesis was common (× 200). D, E DWI and ADC with a b value of 1000 mm2/s showed the tumor was locally obvious restricted diffusion. F Ki-67 was about 30% (× 200)