Fig. 1
From: Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma
PFKFB3 overexpression in proliferating IH tissues and HemECs. A, Heatmap of the 222 differentially expressed genes (DEGs). B, Top 15 Gene Ontology terms enriched in the DEGs. C, Top 15 pathway terms enriched in the DEGs. D, PFKFB3 protein expression in proliferating and involuting IH tissues was detected by immunohistochemistry. E, PFKFB3 protein expression in hemangioma-derived endothelial cells (HemECs) and human umbilical vein endothelial cells (HUVECs) was measured by western blotting. F, PFKFB3 protein expression in hypoxia and normoxia was measured by western blotting. Nor, normoxia; Hpo, hypoxia