Fig. 2
EoE TaMMA confirms EoE-specific traits. A MA plots showing the differential gene expression results expressed as log2(fold change) in the indicated comparisons as a function of log2(average gene expression). Red dots represent genes being differentially expressed with high statistical significance (false discovery rate (FDR) < 1 × 10−5). The number of differentially expressed genes and their trends are indicated in red and blue for the up and down-regulated genes, respectively. B Violin plots showing differential normalized expression of the indicated genes among EoE, GERD, and control esophagi. C, D GO plot showing modulation of biological processes related to epithelial cell proliferation, smooth muscle cell migration, proliferation, differentiation, extracellular matrix remodeling, and chemotaxis between EoE and control (C) and EoE and GERD (D). E, F Violin plots showing differential normalized expression of the indicated genes among EoE, GERD, and control esophagi. The asterisks indicate FDR < 1 × 10−5. G Pearson correlation analysis between CAPN14 and DSG1 expression levels expressed as log2(fold change)