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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: The members of the miR-148/152 family inhibit cancer stem cell-like properties in gastric cancer via negative regulation of ITGA5

Fig. 3

Silencing ITGA5 inhibits the stem cell properties of CD44+EpCAM+ cells. A Numbers of colonies of CD44+EpCAM+ cells following overexpression of ITGA5. B Sphere-forming ability of CD44+EpCAM+ cells examined by sphere-forming assay. C Numbers of migrated CD44+EpCAM+ cells following overexpression of ITGA5. D Viability of CD44+EpCAM+ cells following overexpression of ITGA5 measured by CCK-8 assay. E Drug resistance of CD44+EpCAM+ cells following overexpression of ITGA5 measured by CCK-8 assay. F Expression of CD44, EpCAM and CD24 in CD44+EpCAM+ cells following overexpression of ITGA5 measured by RT-qPCR. *p < 0.05 compared with sh-NC. #p < 0.05 compared with oe-NC

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Journal of Translational Medicine

ISSN: 1479-5876

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