Fig. 7

Landscape of the expression of significantly differentially expressed CRRS’ genes, TMB, TIDE score, Expression of immune checkpoints, and abundance of immune cell infiltration in the TCGA-SKCM cohort. The results were shown in the form of a complex heat map, in which the expression of significantly differentially expressed CRRS’ genes, Expression of immune checkpoints, and the abundance of immune cell infiltration predicted by MCP between the two groups was presented in the form of a heatmap. The TIDE score and TMB are displayed in the form of bar chart and density chart, respectively. The yellow density chart on the right side of the heatmap shows the average of each index. The statistical method of Mann- WhitneyU test was used to compare the two groups. *: P < 0.05; **: P < 0.01; ***: P < 0.001; ****: P < 0.0001