Fig. 12

Drug sensitivity between different signature groups of GDSC and CTRP. A Negative correlation between signature score in GDSC and drug AUC (P < 0.05); B Positive correlation between signature score in GDSC and drug AUC (P < 0.05); C Differences in signature scores of GDSC cell lines with significant negative correlation under different drug treatments; D Differences in signature scores of cell lines with significant positive correlation under different drug treatments in GDSC. E Negative correlation between signature score and DRUG AUC in CTRP (P < 0.05); F Positive correlation between signature score in CTRP and drug AUC (P < 0.05); G Difference in signature scores of all cell lines in CTRP with significant negative correlation under different drug treatments; H Differences in signature scores of all cell lines in CTRP with significant positive correlation under different drug treatments