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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: GSDMD-mediated pyroptosis dominantly promotes left ventricular remodeling and dysfunction in post-myocardial infarction: a comparison across modes of programmed cell death and mitochondrial involvement

Fig. 2

Post-MI mediated cardiac dysfunction and HF. A representative images of transthoracic echocardiography of SHAM and post-MI rats at 5-weeks; B the quantitative analysis of LVEF; C E/A ratio; D LF/HF; E LVESP; F LVEDP; G LVESV; H LVEDV; I SV; J CO; n = 6 per group. All bar charts are expressed as mean ± SEM. *p < 0.05 vs. SHAM. AI, myocardial infarction; LVEF, left ventricular ejection fraction; E/A ratio, early passive diastolic filling to active diastolic filling velocities ratio; LF/HF, low frequency to high frequency ratio; LVESP, left ventricular end-systolic pressure; LVEDP, left ventricular end-diastolic pressure; LVESV, left ventricular end-systolic volume; LVEDV, left ventricular end diastolic volume; SV, stroke volume; CO, cardiac output

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