Fig. 4

Opposite kinetics of [18F]F-FDG and [18F]F-PSMA-1007 in LNCaP-30 and LNCaP-80 cell cultures. A–B display row time activity curves, and mean + SD curves in LANCaP-30 (green) and LANCap-80 (red) cells exposed to [18F]F-FDG for 120 min under the LigandTracer instrument, respectively. C–D display the same curves in LANCaP-30 (green) and LANCap-80 (red) cells exposed to [18F]F-PSMA-1007. E–F show the difference between the two experimental models in terms of number of accessible receptors and receptor-ligand affinity constant, respectively. Data are shown as the mean ± SD. n = 3 experiments per group, with each value defined in triplicate. * = p-value < 0.05; ** = p-value < 0.01