Fig. 1
From: Cucurbitacins as potential anticancer agents: new insights on molecular mechanisms
Summarized scheme with the most representative anticancer molecular mechanisms of cucurbitacins. ↑ increase, ↓decrease; Bax: Bcl-2-associated X protein; Bcl-XL: B-cell lymphoma-extra large; Bcl-2: B-cell lymphoma 2 protein; mTOR: mammalian target of rapamycin protein; VEGFR: vascular endothelial growth factor receptor; VEGF: vascular endothelial growth factor; DNAMT: mitochondrial DNA