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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Calcitriol increases MBNL1 expression and alleviates myotonic dystrophy phenotypes in HSALR mouse models

Fig. 3

In HSALR mice, calcitriol improves muscle histopathology. (a) Representative H&E staining of TA muscles in different groups of mice as indicated. Arrows point to the central nuclei of muscle fibers. Scale bar = 100 μm. (b) The number of fibers with central nuclei was counted in three groups of mice. The data were analyzed by one-way ANOVA followed by Turkey multiple comparison correction. ***p < 0.001. (c) Frequency distribution of cross-sectional TA muscle fiber area was counted in three groups of mice. The mean and SEM (n = 8, 9 and 8 in WT, DM1 0 µg/kg/d and DM1 1 µg/kg/d, respectively) in each group are indicated

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