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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Reconstruction of the gastric cancer microenvironment after neoadjuvant chemotherapy by longitudinal single-cell sequencing

Fig. 3

Changes in T cells and stromal cells before and after NACT. A Expression of cytotoxicity (top panel), proliferation (middle panel), exhaustion (bottom panel) and other T cell functional status-related gene sets in different T cell types before and after NACT. B GSVA of differently expressed pathways in CD4+ T cells (top panel), CD8+ T cells (middle panel), and CD4+ Tregs (bottom panel) before and after NACT. C Volcano plots showing DEGs in CD4+ T cells (top panel) and CD8+ T cells (bottom panel) before and after NACT. D GSVA of differently expressed pathways in endothelial cells (left panel), fibroblasts (middle panel), and myofibroblasts (right panel) before and after NACT. E Volcano plots showing DEGs in fibroblasts (top panel) and myofibroblasts (bottom panel) before and after treatment. *P < 0.05; **P < 0.01; ***P < 0.001; n.s.: not significant

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Journal of Translational Medicine

ISSN: 1479-5876

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