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Table 1 Demographic characteristics of patients

From: CT-based radiogenomic analysis dissects intratumor heterogeneity and predicts prognosis of colorectal cancer: a multi-institutional retrospective study

 

Genomic development dataset

Genomic testing dataset

Radiogenomic dataset

Image testing dataset 1

Image testing dataset 2

n

200

559

236

537

69

Sex (%)

 F

98 (49)

251 (44.9)

101 (42.8)

225 (41.9)

39 (56.5)

 M

102 (51)

308 (55.1)

135 (57.2)

312 (58.1)

30 (43.5)

Tumour grade (%)

 High

16 (8)

–

53 (22.5)

102 (19.0)

–

 Low

29 (14.5)

–

17 (7.2)

30 (5.6)

57 (82.6)

 Middle

155 (77.5)

–

135 (57.2)

167 (31.0)

12 (17.4)

 Unknown

–

–

31 (13.1)

239 (44.4)

–

CEA (%)

 Abnormal

–

–

131 (55.5)

226 (41.6)

43 (62.3)

 Normal

–

–

98 (41.5)

114 (21.0)

26 (37.7)

 Unknown

–

–

7 (3.0)

203 (37.4)

–

TNM stage (%)

 I

28 (14)

32 (5.7)

22 (9.3)

84 (15.6)

–

 II

70 (35)

262 (46.9)

65 (27.5)

188 (34.9)

12 (17.4)

 III

75 (37.5)

202 (36.2)

64 (27.1)

187 (34.8)

41 (59.4)

 IV

27 (13.5)

60 (10.7)

82 (34.7)

79 (14.7)

16 (23.2)

 Unknown

–

3 (0.5)

3 (1.3)

–

–

DFS (months, mean (SD))

42.28(30.10)

48.74(40.38)

37.46 (26.70)

56.76 (35.17)

16.46 (4.26)

Event (%)

 Disease-free

145 (72.5)

379 (67.8)

157 (66.5)

349 (65.0)

41 (59.4)

 Relapse

55 (27.5)

177 (31.7)

79 (33.5)

188 (35.0)

28 (40.6)

 Unknown

–

3 (0.5)

–

–

–