Table 5 Correlation between proteomic-identified proteins in CBPR OVCAR5 cell line and infiltration of immune cells deduced from Go Gene module of TIMER database
Proteomics identified protein | B cells partial correlation p value | CD8+T cells | CD4+ T cells | Macrophages | Neutrophils | Dendritic cells |
|---|---|---|---|---|---|---|
TGFB1 | 0.054 p = 0.123 | 0.162 *p = 0.0003 | 0.178 *p = 0.00084 | 0.193 *p = 0.000019 | 0.214 *p = 2.03254E−06 | 0.187 *p = 0.000034 |
G6PD | 0.008 p = 0.855 | − 0.054 p = 0.235 | 0.034 p = 0.454 | − 0.028 p = 0.526 | 0.061 p = 0.176 | 0.036 p = 0.425 |
FLNA | 0.006 p = 0.889 | 0.186 *p = 0.000 | 0.0326 p = 0.474 | − 0.137 *p = 0.002 | − 0.053 p = 0.242 | − 0.011 p = 0.795 |
ITGAV | 0.102 *p = 0.102 | − 0.103 *p = 0.022 | 0.027 p = 0.549 | 0.077 p = 0.089 | 0.183 *p = 0.000 | 0.159 *p = 0.000 |
ITGA1 | − 0.068 p = 0.132 | 0.051 p = 0.256 | 0.046 p = 0.311 | 0.227 *p = 0.000 | 0.146 *p = 0.001 | 0.122 *p = 0.007 |
ITGA2 | − 0.034 p = 0.456 | 0.075 p = 0.097 | − 0.024 p = 0.595 | − 0.051 p = 0.260 | 0.070 p = 0.124 | 0.090 *p = 0.047 |