Fig. 5

Migratory and proliferative abilities of OVCAR parental and OVCAR5 CBPR cells. A, B The migratory capacity of OVCAR5 parental (1) and OVCAR5 CBPR (2) cells was investigated using a wound healing assay. Representative images of wounds at 0 and 9-h time points. Percentage of wound closure was quantified using Image J software. n = 3; mean ± SD; student’s t test; ***p < 0.01 when compared to OVCAR5 parental cells. C Proliferation in OVCAR5 parental and CBPR cell lines was evaluated by MTT assay over a 24-h period. Wilcoxon matched pair signed rank test; n = 3; *p < 0.05 when compared to OVCAR5 parental cells. D Proliferation in OVCAR5 parental and CBPR cell lines was evaluated by Incucyte live imaging over a 48-h period. 2-way ANOVA with Šídák's multiple comparisons test; n = 5; *p < 0.05 when compared to OVCAR5 parental cells