Fig. 3
From: Integration of CRISPR/Cas9 with artificial intelligence for improved cancer therapeutics
Implications of CRISPR/Cas9 genome engineering for personalized medicine in cancer treatment. Schematic showing the development of the CRISPR-Cas genome engineering platform to identify potential therapeutic targets and design cancer models specific to patient-specific genomic anomalies. CRISPR/Cas9-mediated knock-out, knockin or CRISPR Interference (CRISPRi) screens can be used to identify and validate novel drug targets, tumor-suppressor genes, cancer stem cell-related genes and to elucidate unknown drug resistance mechanisms, thus helping in perosnlized drug designing