Fig. 1
From: HNRNPA2B1-mediated m6A modification of TLR4 mRNA promotes progression of multiple myeloma
Detection of m6A methylation level in MM. A m6A methylation levels in bone marrow from normal controls (n = 15) and MM patients (n = 15) were analyzed via dot blot assay. B Total RNA was extracted from the MM cell line RPMI 8226 for qRT-PCR of “writer”, “eraser” and “reader” genes. C Bone marrow specimens from 13 newly diagnosed MM patients and 13 normal controls were used for RNA extraction followed by qRT-PCR detection of HNRNPA2B1 expression. D–F The expression of HNRNPA2B1 were higher in MM than the counterpart in normal control