Fig. 3

The expression of miR-150-5p in SLE. CircLOC101928570 decreased the c-myb expression A Expression of miR-150-5p in PBMCs from 36 patients with SLE and 25 healthy controls (HCs). B, C Correlation between the expression of miR-150-5p and the SLEDAI score or complement C3 level. D The ROC curve of relative miR-150-5p expression for the 36 different patients with SLE from 25 healthy controls. E, F Expression levels of circLOC101928570 and LOC101928570 in Jurkat cells treated with shRNA-NC, shRNA-circLOC101928570#1, or shRNA-circLOC101928570#2 lentivirus. G, H Expression levels of circLOC101928570 and LOC101928570 in Jurkat cells after transfection with circLOC101928570 lentivirus. I, J Western blot analysis of c-myb proteins after transfection with miR-150-5p mimics, circLOC101928570 overexpression plasmid, circLOC101928570-NC and the miR-150-5p inhibitors shRNA-circLOC101928570#1 and shRNA-NC in Jurkat cells. The results are represented as the mean ± SD (n = 3). NS: no significance, *P < 0.05, **P < 0.01, ***P < 0.001.