Differential regulation of TNFα and IL-6 expression contributes to immune evasion in prostate cancer

Table 1 Infiltration estimates in metastatic vs. pre-metastatic samples across all cohorts

All Cell Type Infiltration Estimates
	BATCH 1			BATCH 2			BATCH 3
Cell	Pval	Localized Mean	Metastatic Mean	Pval	Localized Mean	Metastatic Mean	Pval	Localized Mean	Metastatic Mean
CD4_Treg	0.5993	0.0074	0.0078	0.0349	0.0009	0.0071	0.7618	0.0020	0.0192
CD4_Memory_activated	0.1607	0.1062	0.1147	0.9896	0.1387	0.1270	0.6205	0.0743	0.1032
CD8_Tcell	0.2451	0.0531	0.0421	0.1656	0.0574	0.1026	0.0666	0.0375	0.0641
NKT	0.1366	0.0309	0.0349	0.0139	0.0369	0.0475	0.0289	0.0266	0.0350
Plasma_Cells	0.3206	0.0530	0.0466	0.6358	0.0533	0.0622	0.9597	0.0372	0.0383
CD8_Tcell_GammaDelta	0.2650	0.0080	0.0083	0.4291	0.0042	0.0018	0.0076	0.0345	0.0089
Tcell_follicular_helper	0.2091	0.1206	0.1152	0.0854	0.1403	0.1160	0.1043	0.0988	0.0860
Memory_B_cell	0.9270	0.0053	0.0083	0.3784	0.0367	0.0472	0.8109	0.0029	0.0094
CD4_naive	0.8397	0.0305	0.0314	0.7174	0.0148	0.0154	0.0441	0.0510	0.0298
Naive_B_Cell	0.0757	0.0665	0.0737	0.4079	0.0402	0.0350	0.1000	0.0725	0.0924
M0_Macrophage	0.0370	0.1158	0.1384	0.6492	0.0882	0.0857	0.0770	0.1115	0.1377
Dendritic_cells_resting	0.9709	0.0020	0.0010	0.3646	0.0009	0.0044	0.1051	0.0000	0.0008
Dendritic_cells_activated	0.2340	0.0089	0.0137	0.2952	0.0019	0.0019	0.9831	0.0163	0.0225
M2_Macrophage	0.0057	0.0108	0.0306	0.0146	0.0019	0.0371	0.0189	0.0028	0.0242
M1_Macrophage	0.0393	0.2342	0.1953	0.0162	0.2533	0.1943	0.3011	0.2738	0.2224
Monocytes	0.8895	0.0007	0.0068	0.3143	0.0009	0.0007	0.0234	0.0069	0.0026
Mast_Cells	0.0555	0.1460	0.1311	0.1537	0.1295	0.1141	0.0066	0.1334	0.1033

Wilcoxon ranked sign tests were used to generate p-values. P-values of less than 0.05 are in bold

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