Fig. 5
From: Anthocyanin improves kidney function in diabetic kidney disease by regulating amino acid metabolism
Effect of ANT on the metabolite expression profile in the kidney and serum of db/db mice. The score plot of OPLS-DA for distinguishing the metabolites in the kidney (A) and serum (D) between the ANT and DKD groups. The OPLS-DA model for distinguishing the metabolites in the kidney (B) and serum (E) between the ANT and DKD groups. The upset plot for differentially expressed metabolites among the DKD vs. CT groups, ANT vs. DKD groups, and STEM_trend in the kidney (C) and serum (F). The heatmap for the expression of ANT kidney trend metabolites (G) and ANT serum trend metabolites (H) in the three groups. Bar plot showing the percentage of differentially expressed metabolites among the DKD vs. CT groups, ANT vs. DKD groups, and STEM_trend in the kidney (I) and serum (J)