Table 1 Genetic correlation and polygenic overlap analyses of the SCZ and T2D
Traits | Genetic correlation analysis | Polygenic overlap analysis | ||||||
|---|---|---|---|---|---|---|---|---|
r g ± se | P | P Bonferroni | N SCZ ±se | N T2D ±se | N SCZ−T2D ±se | ρ SCZ−T2D ±se | r g ±se | |
SCZvs T2D (EAS) | -0.054 ± 0.025 | 0.032 | 0.064 | 6566.74 ± 401.14 | 580.35 ± 273.78 | 665.77 ± 259.24 | -0.28 ± 0.17 | -0.049 ± 0.0083 |
SCZ vs T2D (EUR) | -0.098 ± 0.029 | 0.009 | 0.0018 | 8488.47 ± 483.84 | 211.65 ± 205.38 | 1176.33 ± 244.79 | -0.24 ± 0.06 | -0.076 ± 0.0066 |