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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: The p-STAT3/ANXA2 axis promotes caspase-1-mediated hepatocyte pyroptosis in non-alcoholic steatohepatitis

Fig. 1

Bioinformatic analysis of elevated expression of Anxa2/ANXA2 in NASH. (A) Heatmap of differentially expressed genes in GSE55747 dataset. (B) Volcano plot of differentially expressed genes in GSE174478 dataset. The red dots are those differential expression gene with log2Foldchange > 0.585 and P < 0.05

C. Gene Set Enrichment Analysis of ANXA2 in the NAFLD cohort. NES: normalized enrichment score; FDR: false discovery rate. D. Violin plot for the expression of Anxa2 in the Fibrotic and healthy tissues of mice. E. Violin plot for the expression of ANXA2 in the pyroptosis-high and pyroptosis -low NAFLD patients, which are divided by the median value of pyroptosis activity score

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