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Table 2 Uni- and multivariate prognostic analyses for DFS

From: CSPG4 expression in soft tissue sarcomas is associated with poor prognosis and low cytotoxic immune response

Variables

Univariate

Multivariate

N

HR [95% CI]

p-value

N

HR [95% CI]

p-value

Patient's age

303

1.00 [0.99–1.01]

0.839

   

Gender, male vs. female

303

1.04 [0.73–1.48]

0.831

   

Tumor site, head and neck vs. extremity

382

0.00 [0.00- Inf]

0.118

   

Tumor site, internal trunk vs. extremity

 

1.28 [0.90–1.81]

    

Tumor site, superficial trunk vs. extremity

 

0.68 [0.40–1.16]

    

Tumor depth, superficial vs. deep

128

0.26 [0.06–1.07]

0.062

   

Pathological type, leiomyosarcoma vs. UPS

610

2.42 [1.65–3.54]

2.06E−05

55

3.63 [0.28–46.61]

0.322

Pathological type, liposarcoma vs. UPS

 

1.44 [1.00–2.06]

 

55

1.97 [0.10–37.16]

0.650

Pathological type, myxofibrosarcoma vs. UPS

 

1.01 [0.51–2.01]

 

55

7.02 [0.33–150.7]

0.213

Pathological type, other vs. UPS

 

0.78 [0.35–1.72]

 

55

0 [0.00—Inf]

0.999

Pathological tumor size (cm)

142

1.05 [1.02–1.09]

1.39E−03

55

1.07 [0.98–1.17]

0.155

Pathological FNCLCC grade, 3 vs. 1–2

239

1.47 [0.93–2.33]

0.098

55

6.84 [1.04–44.8]

0.045

Genetic profile, complex vs. simple

598

1.17 [0.89–1.54]

0.270

   

CINSARC, high-risk vs. low-risk

610

2.22 [1.70–2.90]

4.35E−09

55

1.14 [0.26–4.93]

0,865

CSPG4, high vs. low

610

1.49 [1.14–1.94]

3.36E−03

55

10.47 [1.04–105.3]

4.62E−02

  1. The significant p-values are in bold
  2. UPS Undifferentiated Pleomorphic Sarcoma, FNCLCC Fédération Nationale des Centres de Lutte Contre le Cancer