Domino hepatocyte transplantation using explanted human livers with metabolic defects attenuates D-GalN/LPS-induced acute liver failure

Table 1 Characteristics of the donated liver tissues and the isolated hepatocytes

Case	Diagnosis	Age (years)	Gender	Indication for LT	Weight (g)	CIT (min)	Viability (%)	Yield (× 10⁶/g)
ZXT	OTCD	4	Female	Recurrent hyperammonemia	154	269	54	14.50
LXY	MMA	2	Male	Recurrent metabolic decompensations	111	390	96	13.33
XCL	Argininemia	13	Male	Recurrent hyperammonemia and neurological damage	321	197	86	6.12
LHZ	OTCD	1	Male	Recurrent hyperammonemia	108	208	96	13.42
AJX	Citrullinemia	1	Female	Recurrent hyperammonemia	158	224	92	7.94
WYH	PA	2	Male	Recurrent metabolic decompensations	169	432	89	8.85
ZYX	Citrullinemia	6	Male	Recurrent hyperammonemia and neurological damage	172	268	91	7.01
ZJN	OTCD	2	Female	Recurrent hyperammonemia and liver function impairment	134	221	94	9.07
HXW	Argininemia	2	Female	Neurological damage	132	303	81	4.43
LJ	FH	5	Male	Severe atherosclerosis refractory to medical therapy	194	243	74	7.32

CIT cold ischemia time, FH familial hypercholesterolemia, LT liver transplantation, MMA methylmalonic acidemia, OTCD ornithine transcarbamylase deficiency, PA propionic acidemia

ISSN: 1479-5876