Fig. 4
From: Silencing eL31 suppresses the progression of colorectal cancer via targeting DEPDC1
Exploration and verification of underlying mechanism of eL31 regulating colorectal cancer. A The heatmap of DEGs identified by PrimeView human gene expression array of HCT 116 cells treated with shCtrl (n = 3) or sheL31 (n = 3). B The enrichment of the DEGs in canonical signaling pathways was analyzed by IPA. C Interaction network diagram between DEGs was analyzed by IPA. D, E The expression of several DEGs were identified by qRT-PCR (D) and western blot (E) experiments in HCT 116 cells with sheL31. F Co-IP assay was used to verify whether there was protein interaction between eL31 and DEPDC1. G The expression of DEPDC1 in tissues of normal and tumor was detected by IHC analysis