Fig. 7

The BCRFS-related CAF signature was an independent prognostic factor and construction and validation of the prognostic nomogram with BCRFS-related CAF signature as one of the parameters. A Univariate and multivariate Cox regression analysis shows the correlation of survival with risk score and various clinical parameters based on GSE116918 dataset. B Univariate and multivariate Cox regression analysis shows the correlation of survival with risk score and various clinical parameters based on TCGA dataset. C The predicted 2-, 3-, 5-year survival rates of prostate cancer patients based on the prognostic nomogram constructed using the risk score and clinicopathological parameters. D ROC analysis showed that the AUCs of nomogram, risk score, tumor stage and gleason score. E Calibration curves show the concordance between predicted and actual 2-, 3-, and 5-year survival rates of patients. CAF: cancer-associated fibroblast; BCRFS: biochemical recurrence-free survival; ROC: receiver operating characteristic; AUC: areas under the ROC curve