Table 2 Univariate analysis of ICR, 3 ir-lncRNA and combination ICR/3 ir-lncRNA model
From: Immune-related 3-lncRNA signature with prognostic connotation in a multi-cancer setting
Cancer | n | ICR signature | 3 ir-lncRNA signature | ICR/3 ir-lncRNA signature | |||
|---|---|---|---|---|---|---|---|
p-value | HR [CI] | p-value | HR [CI] | p-value | HR [CI] | ||
BRCA | 798 | 0.01617 | 0.8636 [0.7664–0.9732] | 0.03408 | 0.4794 [0.2429–0.9463] | 0.01525 | 0.8784 [0.7911–0.9754] |
RAQA | 24 | 0.4672 | 0.8761 [0.6134–1.251] | 0.1813 | 0.2471 [0.03183–1.918] | 0.3824 | 0.8583 [0.6091–1.209] |
HNSC | 417 | 0.007468 | 0.8955 [0.8259–0.9709] | 0.00511 | 0.4609 [0.268–0.7926] | 0.005836 | 0.9024 [0.8388–0.9707] |
SKCM | 216 | 0.000243 | 0.8287 [0.7496–0.9162] | 0.002382 | 0.4238 [0.2435–0.7374] | 0.000243 | 0.8496 [0.7787–0.9269] |
UCEC | 311 | 0.1505 | 0.8485 [0.6783–1.061] | 0.009155 | 0.2662 [0.0984–0.7202] | 0.09279 | 0.8458 [0.6958–1.028] |
LIHC | 191 | 0.0983 | 0.89 [0.7752–1.022] | 0.05554 | 0.4662 [0.2134–1.018] | 0.07708 | 0.8926 [0.7869–1.012] |
STAD | 247 | 0.2773 | 0.9391 [0.8385–1.052] | 0.7487 | 1.173 [0.4419–3.114] | 0.3354 | 0.9506 [0.8575–1.054] |
BLCA | 248 | 0.3766 | 0.9567 [0.8672–1.055] | 0.6954 | 0.8875 [0.4884–1.613] | 0.4031 | 0.964 [0.8845–1.051] |
CESC | 190 | 0.03583 | 0.8286 [0.6951–0.9876] | 0.04873 | 0.2908 [0.08516–0.993] | 0.03316 | 0.8413 [0.7177–0.9863] |
KICH | 65 | 0.5425 | 0.8991 [0.6385–1.266] | 0.9452 | 0.9403 [0.1623–5.447] | 0.5853 | 0.9214 [0.6868–1.236] |
OV | 249 | 0.6857 | 0.9801 [0.8893–1.08] | 0.6233 | 1.14 [0.6766–1.919] | 0.7909 | 0.9888 [0.9101–1.074] |
LUSC | 202 | 0.2156 | 0.9207 [0.8079–1.049] | 0.6961 | 0.8491 [0.3738–1.929] | 0.2505 | 0.9352 [0.8341–1.048] |
READ | 44 | 0.1527 | 0.3151 [0.06472–1.534] | 0.2701 | 0.0752 [0.00076–7.467] | 0.1497 | 0.3248 [0.07033–1.5] |
COAD | 112 | 0.9295 | 1.012 [0.7783–1.316] | 0.9982 | 0.998 [0.1777–5.604] | 0.9357 | 1.01 [0.7939–1.285] |
LUAD | 469 | 0.8737 | 0.993 [0.9108–1.083] | 0.4199 | 0.7292 [0.3384–1.571] | 0.8207 | 0.9908 [0.9148–1.073] |
GBM | 150 | 0.5058 | 1.043 [0.9216–1.18] | 0.536 | 1.251 [0.6153–2.545] | 0.4844 | 1.041 [0.9308–1.163] |
KIRP | 188 | 7.63E-05 | 1.511 [1.231–1.853] | 0.003328 | 26.28 [2.964–233.1] | 5.14E-05 | 1.477 [1.223–1.784] |
KIRC | 298 | 0.1702 | 1.094 [0.9621–1.245] | 0.3038 | 2.016 [0.5298–7.672] | 0.1689 | 1.088 [0.9648–1.227] |
LGG | 478 | 3.14E-09 | 1.37 [1.234–1.52] | 5.82E-07 | 6.528 [3.128–13.63] | 7.04E-10 | 1.341 [1.222–1.472] |