Fig. 1
From: Loss of endothelial EMCN drives tumor lung metastasis through the premetastatic niche
The downregulation of EMCN expression is related to metastasis and recurrence in lung cancer patients. A Heatmap of differentially expressed genes in lung cancer from TCGA datasets. B Volcano plot of differentially expressed mRNAs. Red dots represent upregulated mRNAs, and blue dots represent downregulated mRNAs. C EMCN expression levels in adjacent tissues and tumor tissues were analyzed (Wilcox tests, ****p < 0.0001, **p < 0.01, **p < 0.05). D EMCN gene expression levels in metastatic patients and normal tissues in the TCGA dataset (Wilcox tests, ****p < 0.0001). E EMCN gene expression levels in recurrence patients and normal tissues in TCGA dataset (Wilcox tests, ****p < 0.0001)