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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: miR-1297 sensitizes glioma cells to temozolomide (TMZ) treatment through targeting adrenomedullin (ADM)

Fig. 1

ADM is specifically up-regulated in TMZ-resistant glioblastoma cell strains. A The expression of ADM in untreated glioblastoma stem cells (GSCs) and GSCs that survived after 500uM temozolomide (TMZ) treatment, according to GSE68029. B The expression of ADM in induced TMZ-resistant LN229 cells and regular LN229 cells, according to GSE113510. C The expression of ADM in TMZ treatment sensitive glioblastoma stem cell clones and TMZ treatment resistant glioblastoma stem cell clones according to GSE46531. D The expression of ADM in samples with or without radiation-therapy, according to TCGA-GBMLGG. E ADM expression was determined in a normal human glial cell line SVG p12 and four glioma cell lines, U87-MG, A-172, LN-229, and T98G using qRT-PCR

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Journal of Translational Medicine

ISSN: 1479-5876

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