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Table 2 Female age-stratified comparison of clinical outcomes

From: Clinical application of noninvasive chromosomal screening for elective single-blastocyst transfer in frozen-thawed cycles

Age of female

NICS results

Ratio

Clinical pregnancy rate

Miscarriage rate

Ongoing pregnancy rate

Live birth rate

 < 35 years old (n = 168)

Euploid

45.2% (76/168)

60.5% (46/76)

15.2% (7/46)

51.3% (39/76)

50.0% (38/76)

Aneuploid

26.2% (44/168)

38.6% (17/44)

17.6% (3/17)

29.5% (13/44)

29.5% (13/44)

Chaotic/NA

28.6% (48/168)

62.5% (30/48)

16.7% (5/30)

52.1% (25/48)

52.1% (25/48)

p-value

 

0.034

0.999

0.041

0.050

 ≥ 35 years old (n = 42)

Euploid

31.0% (13/42)

30.8% (4/13)

25.0% (1/4)

23.1% (3/13)

23.1% (3/13)

Aneuploid

57.1% (24/42)

12.5% (3/24)

33.3% (1/3)

8.3% (2/24)

8.3% (2/24)

Chaotic/NA

11.9% (5/42)

40.0% (2/5)

50.0% (1/2)

20.0% (1/5)

20.0% (1/5)

p-value

 

0.241

0.999

0.344

0.344

P value for age subgroups

 < 0.001

 < 0.001 (55.4%vs21.4%)

0.194 (16.1%vs 33.3%)

 < 0.001 (45.8%vs 14.3%)

 < 0.001 (45.2%vs 14.3%)