Table 5 The eight proteins involved the mainly KEGG pathways which those may associated with the etiology of CSCC development in our proteomics results
Protein | KEGG pathways |
|---|---|
TNC | Focal adhesion; ECM-receptor interaction; Human papillomavirus infection; MicroRNAs in cancer; PI3K-Akt signaling pathway |
FSCN1 | MicroRNAs in cancer |
SERPINB1 | No enriched pathways |
ACTN1 | Focal adhesion; Viral carcinogenesis; Tight junction; Regulation of actin cytoskeleton; Adherens junction; Leukocyte transendothelial migration |
RAB31 | Endocytosis |
COL3A1 | Relaxin signaling pathway; Protein digestion and absorption; Platelet activation |
COL1A1 | Focal adhesion; Relaxin signaling pathway; Protein digestion and absorption; ECM-receptor interaction; Human papillomavirus infection; Proteoglycans in cancer; PI3K-Akt signaling pathway; Platelet activation |
CD36 | PPAR signaling pathway; Phagosome; ECM-receptor interaction; AMPK signaling pathway |