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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Gene signatures, immune infiltration, and drug sensitivity based on a comprehensive analysis of m6a RNA methylation regulators in cervical cancer

Fig. 1

Overall expression of m6A-related genes in patients with CESC. A Workflow of the study. B Mutation map of m6A-related genes in TCGA-patients with CESC. Samples were sequenced according to the burden of nonsynonymous mutations in somatic cells, and genes were sequenced according to the mutation frequency. Different colors indicate different mutation types. The section above the legend shows the mutation load; C CNV differential changes and locations of m6A-related genes on 23 chromosomes of patients with TCGA-CESC; D change frequency of CNV level of m6A-related genes, where red represents CNV level amplification and green represents CNV level deletion; E PCA showed differences between cervical and normal cervical tissues before and after combination and batch effect removal in TCGA, GTEx, and GEO datasets. The left panel shows the result before batch effect removal, and the right shows the result after batch effect removal. F Differentially expressed m6A-related genes in cervical cancer and normal cervical tissue; G expression correlation analysis of m6A-related genes in CESC

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