Fig. 3

Increased levels of Sirtuins and p53 and reduced levels of p21 as well of miR-146b expression were observed in MSCs in presence of sera collected in subjects after the training (b, BN) and NC4000 performance (c, AN). a (BPP, before the preparation period); b (BN, the week before NC4000); AN (c, 10 days after NC4000). *p < 0.05; **p < 0.005