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Table 5 Prediction of discontinuous B-cell epitopes of ODAC vaccine. The conformational epitopes were predicted using ElliPro

From: In silico designing of a novel epitope-based candidate vaccine against Streptococcus pneumoniae with introduction of a new domain of PepO as adjuvant

Epitopes

Residues

Number of residues

Score

1

S296, E299, V300, K301, K302, A303, E304, F305, E306, L307, V308, K309, E310, E311, A312, K313, E314, P315, R316, N317, E318, E319, K320, V321, K322, Q323, A324, K325, A326, K327, V328, E329, S330, K331, K332, A333, V334, A335, T336, R337, N340, I341, D344, K347

44

0.819

2

M1, T2, R3, Y4, Q5, D6, D7, Y9, D10, A11, I12, N13, G14, E15, W16, Q17, Q18, T19, A20, E21, I22, P23, A24, D25, K26, S27, Q28, T29, G30, G31, F32, V33, D34, P57, E58, H69, R70, V72, R73, D74, F75, D76, K77, R78, E79, A80, D81, G82, I83, T84, P85, V86, A357, E358, E359, K361, V362, K363, E364, K365, G366, H367, H368, H369, H370, H371, H372

67

0.724

3

L51, A52, G53, E54, A114, A115, A116, K117, A118, A119, Q120, A121, Y122, A123, K124, E125, K126, G127, L128, T129, P130, P131, S132, T133, D134, H135, Q136, D137, S138, G139, N140, T141, E142, A143, K144, G145, E147, V174, K175, N176, G177, S178, G179, G180, S181, S182, S225, A226, K227, D228, P229, N230, N231, K232, E233, F234, E236, K237

58

0.715

4

V159, P160, D162, R163

4

0.595

5

D255, N258, K259

3

0.591

6

I260, P261, A262, E263, K264, K265, P282, S283

8

0.579