Fig. 10

RMS fluctuation values as a function of residue number for the vaccine-receptor complexes. A RMSF plots for the vaccine and TLR2 are depicted in yellow and orange, respectively. The plots reveal that the vaccine residues except for 112 residues of PepO have a greater degree of flexibility than that of TLR2. B RMSF plots for the vaccine and TLR4 are represented in yellow and green, respectively. The ODAC and TLR4 residues show no significant flexibility