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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Probiotics ameliorate IgA nephropathy by improving gut dysbiosis and blunting NLRP3 signaling

Fig. 3

a, b Glomerular IgA immunofluorescence and the average fluorescence intensity of IgA in mouse kidney. c. PAS staining of wild-type normal controls (WC group), wild-type mice with IgAN (W-IgAN group), W-IgAN treated with probiotics (W-IgAN + B group), NLRP3−/− mice (NC), NLRP3.−/− mice with IgAN (N-IgAN), and N-IgAN treated with probiotics (N-IgAN + B). d, e The urinary protein/creatinine ratio and serum creatinine levels of the mice in different groups. f–h The serum inflammatory indicators of each group were measured by enzyme-linked immunosorbent assay. ik The results of the immunofluorescence test and qPCR of collagen 1 in kidney tissue. * 0.01 < P ≤ 0.05. ** 0.001 < P ≤ 0.01. *** P ≤ 0.001

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