Fig. 2

Joint associations of healthy lifestyle score and mental health on mortality among US cancer survivors. A HR (95% CI) for all-cause mortality. B HR (95% CI) for non-cancer mortality. Mental health was assessed using PHQ-9. Weighted Cox regression models were used to estimate the HR (the solid symbols) with 95% CI (the error bars) of joint categories of healthy lifestyle score and mental health for mortality. The following covariates were adjusted: age at the time of interview, sex, education level, ratio of family income to poverty, race and ethnicity, sleep duration, prevalent diabetes, hypertension, dyslipidemia, history of cardiovascular disease, the number of cancer types, age at the first cancer diagnosis. Additive interaction effects between the lifestyle score (0–1 point vs. 3–5 points) and mental health (PHQ-9 score ≥ 10 vs. PHQ-9 score = 0–4) were evaluated. PHQ-9 Patient Health Questionnaire, HR hazard ratios, CI confidence interval; RERI relative excess risk due to interaction; AP attributable proportion, S synergy index