Fig. 3

IO Score Positivity Among TIME Phenotype and Confirming Binary IO Score Threshold A Percentage of IO Score positive cases in each TIME phenotype (IM, MSL, and M); B Calculation of a new theoretical threshold for positivity of the IO Score. Positive IO Score in the IM phenotype and negative scores in the M and MSL phenotypes are considered true positives and true negatives, respectively. Using the intersection of sensitivity and specificity where both the actual threshold and the new theoretical threshold are then used to calculate overall accuracy