Fig. 7

A-C represent the statistical results of the concentration of serum EPI, NE, and COR, respectively, in the two groups of rats at six time points in 24 h. D–J represent the relative expression of the myocardial β1-AR, α1-AR, Gr, Bmal1, Per2, Clock, and Creb1 respectively, in the two groups of rats at six time points in 24 h. The two independent samples t-test was used to compare the two groups at each time point. *p < 0.05, **p < 0.01, ***p < 0.001. (C1-C15) represent the correlation analysis between the two factors, respectively. The U represents a two-way clustering heat map of gene expression in myocardial tissue, which is classified using a hierarchical clustering method. Red represents low relative expression, and green represents high relative expression. The V represents the Bayesian network diagram of the interaction between CM and myocardial genes calculated using the heuristic mode. When there is a line between two factors, it indicates that the two factors have a causal relationship (Parents-Descendants), the arrow points to the result (Descendants), and the other end of it is the cause (Parents)