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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Interplay of Helicobacter pylori, fibroblasts, and cancer cells induces fibroblast activation and serpin E1 expression by cancer cells to promote gastric tumorigenesis

Fig. 2

Transcription profiles between NFs and CAFs by RNA-seq analysis. A Venn diagram and bar plot show the shared 161 DEGs between three-pared CAFs and NFs isolated from cancer tissues and adjacent normal tissues of three patients with gastric adenocarcinoma. B Top 10 GO enrichment analyses of 161 DEGs. C Heatmap depicts the results of hierarchical clustering analysis based on 161 DEGs between CAFs and NFs. D KEGG pathway enrichment analyses of 161 DEGs. E PPI analysis reveals that p53-associated proteins are down-regulated, while SPARC-associated proteins are up-regulated in CAFs compared to NFs. F Up-regulated pathways and down-regulated pathways in the GESA

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Journal of Translational Medicine

ISSN: 1479-5876

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