Table 1 Correlation analysis between PROS1 and gene markers of immune cells in TIMER and GEPIA

B cell

CD19

7.11E − 06

4.2E − 08

CD79A

1.46E − 02

2.3E − 04

T cell

CD3D

1.01E − 18

1E − 15

CD3E

2.59E − 20

6.4E − 22

CD2

1.93E − 26

2.6E − 30

CD8 + T cell

CD8A

9.38E − 06

2.9E − 07

CD8B

2.95E − 05

1.9E − 06

CD4 + T cell

CD4

6.8E − 12

6.8E − 22

Monocyte

CD86

8.38E − 15

3.1E − 17

CSF1R

1.55E − 06

1.2E − 07

TAM (general)

CCL2

6.00E − 16

4.5E − 16

CD68

3.5E − 25

3.5E − 25

IL10

4.17E − 15

1.1E − 18

M1

IRF5

5.12E − 12

3.7E − 13

PTGS2

3.87E − 02

3.9E − 02

NOS2

2.3E − 03

1.4E − 02

M2

CD163

4.3E − 24

4.3E − 24

VSIG4

8.18E − 12

2.5E − 13

MS4A4A

2.8E − 29

2.8E − 29

Neutrophils

CEACAM8

8.2E − 01

9.7E − 01

ITGAM

8.97E − 11

8.6E − 12

CCR7

3.68E − 14

6.8E − 16

Natural killer cell

KIR2DL1

5.1E − 03

2.7E − 04

KIR2DL3

3.79E − 07

1.2E − 08

KIR2DL4

8.55E − 08

1.8E − 10

KIR3DL1

1.3E − 02

3E − 04

KIR3DL2

1.9E − 02

1.3E − 04

KIR3DL3

9.7E − 01

6.6E − 01

KIR2DS4

3.52E − 05

1.1E − 05

Dendritic cell

HLA-DPB1

1.6E − 33

1.6E − 33

HLA-DQB1

6.5E − 15

6.5E − 15

HLA-DRA

4.6E − 38

4.6E − 38

HLA-DPA1

7.7E − 38

7.7E − 38

CD1C

8.18E − 17

8.2E − 16

NRP1

3.43E − 33

1.5E − 34

ITGAX

1.51E − 07

1.2E − 07

Microglia

CX3CR1

7.78E − 07

1.6E − 07

P2RY12

8,75E − 02

0.02

ITGAX

1.51E − 07

1.2E − 07

FCGR1A

2.34E − 11

3.9E − 09

TMEM119

2.6E − 06

6.3E − 08

CD33

1.25E − 14

1E − 13

Monocyte-derived Macrophages

MRC1

2.4E − 02

0.16

CD163

P < 0.001

4.3E − 24

CD14

1.23E − 17

7.2E − 19

TEK

4.49E − 01

0.84

THBD

1.14E − 08

3.7E − 11

ICAM1

1.69E − 24

2.2E − 26

ITGA4

P < 0.001

1.4E − 32