Fig. 10

PROS1 increased the proliferation, invasion of GBM cells in vitro. A qRT-PCR assays were applied to analyse the expression level of PROS1 after transfection by sh PROS1 or PROS1 overexpression vector for 24 h in U87 or U251 cells. B Cell viability of U87 or U251 cells after knocking down or overexpressing PROS1 was determined using CCK8 assays. C Colony formation assay were performed in transfected U87 or U251 cells to evaluate cell proliferation ability. D Transwell assays were performed in transfected U87 or U251 cells to evaluate cell invasion ability (Magnification: × 100). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. Error bars indicate mean ± SD