| Univariable analysis | Multivariable analysis | ||||
---|---|---|---|---|---|---|
Variable | HR | 95%CI | P value | HR | 95%CI | P value |
Age | ||||||
 ≥ 60 or < 60 | 1.0855 | 0.7524–1.5658 | 0.6609 | 1.3874 | 0.9432–2.0410 | 0.0963 |
Sex | ||||||
 Male or female | 1.1320 | 0.8254–1.5525 | 0.4419 | 0.9599 | 0.6849–1.3455 | 0.8125 |
Smoking history | ||||||
 Yes or no | 0.9332 | 0.6030–1.4444 | 0.7565 | 1.04711 | 0.6408–1.7110 | 0.8542 |
T stage | ||||||
 1, 2, 3 or 4 | 1.9309 | 1.4885–2.5049 |  < 0.0001 | 1.1945 | 0.9648–1.4790 | 0.1029 |
Lymphatic metastasis | ||||||
 Yes or no | 1.0001 | 0.8281–1.2096 |  < 0.0001 | 1.2839 | 0.9116–1.8082 | 0.1526 |
TNM stage | ||||||
 I, II, III or IV | 1.5867 | 1.3685–1.8396 |  < 0.0001 | 1.3638 | 1.1063–1.6811 | 0.0037 |
EGFR status | ||||||
 MUT or WT | 1.4752 | 0.9718–2.2394 | 0.0679 | 1.4295 | 0.9034–2.2620 | 0.1270 |
KRAS status | ||||||
 MUT or WT | 1.2462 | 0.8864–1.7521 | 0.2054 | 1.3121 | 0.9148–1.8820 | 0.1397 |
Risk score | ||||||
 High or low | 2.5718 | 1.6286–4.0612 |  < 0.0001 | 2.5167 | 1.5408–4.1107 | 0.0002 |