A novel immune checkpoints-based signature to predict prognosis and response to immunotherapy in lung adenocarcinoma

Table 1 Clinical characteristics of the patients from multiple institutions

Characteristics	TCGA n = 502	GSE11969 n = 90	GSE30219 n = 83	GSE31210 n = 226	GSE37745 n = 106	GSE50081 n = 127	GSE68465 n = 442	GSE81089 n = 105	Independent n = 102
Age, year
≥ 60	356	58	46	130	64 42	108 19	314	87	53
< 60	136	32	37	96	42	19	128	18	49
NA	10	0	0	0	0	0	0	0	0
Sex
Male	231	47	65	105	46	65	223	37	56
Female	271	43	18	121	60	62	219	68	46
Smoking history
Yes	72	45	NA	111	NA	92	300	94	60
No	416	45	NA	115	NA	23	49	11	43
NA	14	0	NA	0	NA	12	93	0
TNM stage
I and II	389	65	81	226	89	127	371	78	79
III and IV	105	25	2	0	17	0	68	27	23
NA	8	0	0	0	0	0	3	0	0
OS state
Alive	320	50	43	35	77	51	236	48	76
Death	182	40	40	191	29	76	206	57	26

ISSN: 1479-5876