Fig. 5

KO of SDC4 altered the PKC-α-ABCA1-ABCG1 pathway in cultured macrophages. a Representative western blots of PKC-α, ABCA1, ABCG1, and densitometric analysis of ApoE^−/− + Saline, ApoE^−/−SDC4^−/− + Saline, ApoE^−/− + ox-LDL, and ApoE^−/−SDC4^−/− + ox-LDL macrophages treated with or without ox-LDL for 48 h (n = 5). b Representative western blots of PKC-α, ABCA1, ABCG1 and densitometric analysis of ApoE^−/−, ApoE^−/−SDC4^−/− + Vector, ApoE^−/−SDC4^−/− + SDC4 macrophages (n = 5). c Representative western blots of PKC-α, ABCA1, ABCG1 and densitometric analysis of ApoE^−/− + Saline, ApoE^−/−SDC4^−/− + Saline, ApoE^−/−SDC4^−/− + ox-LDL, and ApoE^−/−SDC4^−/− + ox-LDL + PDBu macrophages (n = 5)