Fig. 2

Gross wound healing measures. A Representative images of healing progression of excisional wounds by treatment condition. B Wound size quantification indicates DFO treated IR wounds showed accelerated wound closure relative to vehicle and IR untreated wounds but slower than nonirradiated wounds (n = 10 per condition). C Wound size at POD14 shows statistically significant smaller wounds in DFO treatment (mean 10.34%) than vehicle (22.38%;**p < 0.01) and IR untreated wounds (18.71%;*p < 0.05) while nonirradiated wounds had closed (0.03%;**p < 0.01). D Vehicle and IR untreated wounds had a higher rate of non-healing (n = 3) than DFO treated irradiated wounds (n = 1) at POD21. Nonirradiated wounds all closed. DFO: deferoxamine; IR: irradiation; POD: post-operative day; ns: not significant