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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Tumor-suppressive MEG3 induces microRNA-493-5p expression to reduce arabinocytosine chemoresistance of acute myeloid leukemia cells by downregulating the METTL3/MYC axis

Fig. 7

MEG3 promotes the sensitivity of AML cells to AraC in vivo. A, Quantitative analysis of bioluminescence imaging to determine the luminescence intensity. B, The expression of MEG3, miR-493-5p, METTL3 and MYC in the bone marrow samples of mice determined by RT-qPCR. C, Content of AML cells in liver, spleen, and femur tissues of mice detected by IHC. * p < 0.05. n = 8

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